The cell cycle: what it is, how it has been studied and how it will be studied

Il ciclo cellulare: cos’è, come è stato e come sarà studiato


The cell cycle has a pivotal role in many aspects of cell’s life. The metabolic state of the cell and its decision to proliferate or even to die, as well as physiological or pathological conditions, are some of the aspects deeply influenced by the cell cycle and that, in their turn, influence it. The molecular basis of this extremely complex process has been extensively studied, nevertheless a lot of information is still missing. Indeed, old widely applied techniques as thymidine analogues incorporation have been shown to be inadequate in many current experimental settings or if employed with new scientific methodologies. Conversely, new tools recently developed, as the FUCCI technology, are a great promise and will enable to deepen our comprehension of the cell cycle by allowing scientists to study it in vivo through live imaging. With this contribution, the basis of the cell cycle and of its regulation as well as old and new techniques to study it, will be revised.

G Tec Nefrol Dial 2015; 27(2): 115 - 119


Article Subject: BIOTECNOLOGIA



Sara Nardi, Duccio Lombardi

Article History

This article is available as full text PDF.

  • If you are a Subscriber, please log in now.

  • Article price: Eur 36,00
  • You will be granted access to the article for 72 hours and you will be able to download any format (PDF or ePUB). The article will be available in your login area under "My PayPerView". You will need to register a new account (unless you already own an account with this journal), and you will be guided through our online shop. Online purchases are paid by Credit Card through PayPal.
  • If you are not a Subscriber you may:
  • Subscribe to this journal
  • Unlimited access to all our archives, 24 hour a day, every day of the week.


  • Nardi, Sara [PubMed] [Google Scholar]
    Unità di Nefrologia, Ospedale Universitario Pediatrico Meyer, Firenze
  • Lombardi, Duccio [PubMed] [Google Scholar]
    Dottorando in Area del Farmaco e Trattamenti Innovativi, Dipartimento di Medicina Sperimentale e Clinica, Centro d’Eccellenza DENOTHE, Università degli Studi di Firenze, Firenze

Article usage statistics

The blue line displays unique views in the time frame indicated.
The yellow line displays unique downloads.
Views and downloads are counted only once per session.

No supplementary material is available for this article.